In reference to yesterday’s #allergyhour on twitter, the topic of the influenza vaccination came up and I got inspired to post the latest developments in regards to the flu vaccine’s application, safety and allergenic potential.
In the UK, the flu vaccine is currently administered to high risk children (kids with comorbidities such as severe asthma) only and requires an intramuscular jab. From 2014, an annual influenza vaccine for all children will be introduced into the UK immunisation schedule, to reduce the morbidity and mortality associated with this disease. This new vaccine, known as LAIV (Live Attenuated Intranasal Vaccine) is given by a spray into the nose and has been successfully used in the US for a couple of years. You can see the results of a NEJM study here. The new vaccine is grown in hen’s eggs and contains egg protein, and there are NO existing data on the safety of LAIV in egg- allergic children. To prove the safety of the intranasal vaccine for egg allergic children, the SNIFFLE study will be performed in a multicentre setting shortly. The new application sounds very promising and I am looking forward to the results. Will keep you posted.